The Department of Computer Science at the University of Cyprus cordially invites you to the Colloquium entitled:

Digital Microfluidic Biochips: A Vision for Cyberphysical Systems, Functional Diversity and More than Moore


Speaker: Prof. Krishnendu (Krish) Chakrabarty
Affiliation: Duke University, USA
Category: Colloquium
Location: Room 148, Faculty of Pure and Applied Sciences (FST-01), 1 University Avenue, 2109 Nicosia, Cyprus (directions)
Date: Wednesday, May 4, 2011
Time: 16:00-17:00 EET
Host: Theocharis Theocharides (ttheocharides AT and Costas Pattichis (pattichi AT

Microfluidics-based biochips (or lab-on-chip) are revolutionizing laboratory procedures, and leading to a convergence of information technology with biochemistry and microelectronics. Advances in microfluidics technology offer exciting possibilities for high-throughput DNA sequencing, drug discovery, immunoassays, neo-natal and point-of-care clinical diagnostics, etc. As microfluidic lab-on-chip mature into multifunctional devices with "smart" reconfiguration and adaptation capabilities, automated design and ease of use become extremely important. Computer-aided design (CAD) tools are needed to allow designers and users to harness the new technology that is rapidly emerging for integrated biofluidics. This talk will present research at Duke University on design automation and software control for microfluidic biochips. First, the speaker will provide an overview of electrowetting-based digital microfluidic biochips. Next, the speaker will describe synthesis methods that can map bioassay protocols to a reconfigurable microfluidic device and generate an optimized schedule of bioassay operations, the binding of assay operations to functional units, and the layout and droplet flow-paths for the biochip. Techniques for pin-constrained chip design, fault detection, and dynamic reconfiguration will also be presented. Finally, future directions involving a cyberphysical systems perspective will be highlighted.

Short Bio:
Krish Chakrabarty is a Professor of Electrical and Computer Engineering at Duke University. His current research is focused on design and test of system-on-chip integrated circuits, microfluidics-based biochips (digital microfluidics, microelectrofluidics), and wireless/sensor networks. Research support is provided by the National Science Foundation, the Semiconductor Research Corporation, Cisco Systems, HP Labs, Intel Corporation (equipment grant), and the National Institutes of Health (STTR Phase II subcontract from Advanced Liquid Logic). Other sponsors in the recent past have included DARPA and the Office of Naval Research. Prof. Chakrabarty is a Fellow of IEEE, a Golden Core Member of the IEEE Computer Society, a Distinguished Engineer of ACM, a member of SIGDA, and a member of Sigma Xi. He is also an Invitational Fellow of the Japan Society for the Promotion of Science (JSPS), 2009. He is a recipient of the IEEE Computer Society Meritorious Service Award. Prof. Chakrabarty is a Chair Professor (Member of the Chair Professor Group in Software Theory) in the School of Software in Tsinghua University, Beijing, China.

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Sponsor: The CS Colloquium Series is supported by a generous donation from Microsoft